With a captip to AliceAnna57, we find the following:
Carlos Lee makes 26.9% of the Astros' total payroll. This is the largest chunk of payroll that one player takes up in all of baseball.
If you went on other payrolls, Carlos Lee would make 38.6% of the Indians' payroll, 52.6% of the Royals' payroll, or 9.4% of the Yankees' payroll.